Normal reference values for Tc-99m pertechnetate thyroid uptake in northern Iranian population: A single-center experience

TL;DR

This study establishes normal reference values for Tc-99m pertechnetate thyroid uptake in a northern Iranian population.

Contribution

Provides region-specific reference values for thyroid uptake in northern Iran.

Findings

The median thyroid uptake was 0.9% with a range of 0.54–1.80%.

Reference values vary by geography and dietary iodine intake.

Periodic regional updates to uptake values are recommended.

Abstract

The normal reference values for the thyroid uptake of radioactive iodine and Tc-99m pertechnetate in euthyroid patients vary by geographical location as well as the amount of iodine intake in the diet. The present study examines the normal reference values for thyroid uptake of Tc-99m pertechnetate in the North of Iran.

The participants of this study were 64 patients (all over 20 years of age) who had referred to the Nuclear Medicine Center of the Shahid Beheshti Hospital for thyroid scan over the period between March 2018 and May 2020. It is worth mentioning that relying on laboratory test results, only patients with normal thyroid function were included in this cross-sectional study.

The median, the 5th and 95th percentiles and thyroid uptake range of 99mTc-pertechnetate in euthyroid patients were 0.9, 0.6 to 1.8% and 0.54 - 1.80%, respectively.

The percentage of uptake in the thyroid gland in each geographical area varies based on race and diet content, so it is necessary to determine the percentage of uptake in each specific region and even check it periodically.

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