Association between parities and duration of breastfeeding and the severity of coronary artery disease in women above 30 years old age (A pilot study)

TL;DR

This pilot study explores how the number of live births and breastfeeding duration may relate to the severity of coronary artery disease in women over 30.

Contribution

The study is a pilot investigation into the potential link between reproductive history and coronary artery disease severity in women.

Findings

Women with more than 5 live births tended to have higher coronary artery disease severity.

The association between live births and disease severity was not significant after adjusting for age.

Breastfeeding duration was not analyzed as a significant factor in this study.

Abstract

The prevalence and mortality of CVD in women increase over time. We conducted this research to evaluate the severity of coronary artery disease with the number of live births and breastfeeding duration.

Patients aged 30-50 years old with positive exercise tests or evidence of cardiac ischemia who were candidates for coronary angiography were included. All the participants had at least one child. Syntax score was used to evaluate the severity of coronary arteries.

Mean number of children was 3.72±1.85, in those patients with <2 live births no one had a syntax score≥1, but in the>5 live births group most patients had a syntax score≥1. In patients with zero syntax score, it was estimated as 4.91±39.7; in patients with 1≤ syntax score, it was 4.48±7.29 (P =0.76). Among patients with > 5 birth lives, those with higher syntax scores had older ages (P=0.497). After adjusting age, the association between live births and syntax score became non-significant (P=0.850).

By increasing the number of live births >5, the severity of coronary artery disease, increases. However, this association was not significant after adjusting the age of patients.

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