# Epstein-Barr Virus (EBV)-Associated Myopericarditis Provoking Severe Heart Failure in an Immunocompetent Young Male

**Authors:** Edwin R Mosquea Gomez, Vanessa Castellanos, Isaac Soliman, Bijal Mehta

PMC · DOI: 10.7759/cureus.62315 · Cureus · 2024-06-13

## TL;DR

A young, healthy man developed severe heart failure due to Epstein-Barr virus-induced myopericarditis, a rare condition in immunocompetent individuals.

## Contribution

This case report highlights the rare occurrence of EBV-associated myopericarditis in an immunocompetent young adult.

## Key findings

- A 28-year-old immunocompetent male developed severe heart failure from EBV-induced myopericarditis.
- The patient was treated with NSAIDs, colchicine, and heart failure medications, with planned close follow-up.
- This case underscores the importance of considering viral etiologies in young patients with unexplained heart failure.

## Abstract

Myopericarditis, a rare inflammatory condition affecting the heart and its surrounding layers, can lead to serious consequences if not promptly diagnosed and treated. A recent case involved a 28-year-old man with no significant medical history who developed severe chest pain and was diagnosed with myopericarditis induced by the Epstein-Barr virus (EBV). The patient's symptoms, imaging, and lab test results suggest myopericarditis. Initially, he was treated with non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine, and upon discharge, he continued with NSAIDs, as well as guideline-directed medical therapy, including an angiotensin-converting enzyme inhibitor, beta blocker, and SGLT2 inhibitor. Close follow-up with the cardiology and heart failure programs was planned. This case highlights the rare occurrence of this condition in individuals with a healthy immune system.

## Linked entities

- **Chemicals:** colchicine (PubChem CID 2833), angiotensin-converting enzyme inhibitor (PubChem CID 443376)
- **Diseases:** heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** chest pain (MESH:D002637), Heart Failure (MESH:D006333), Myopericarditis (MESH:D010146), inflammatory (MESH:D007249)
- **Chemicals:** colchicine (MESH:D003078)
- **Species:** human gammaherpesvirus 4 (Epstein Barr virus, no rank) [taxon 10376], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11246102/full.md

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Source: https://tomesphere.com/paper/PMC11246102