# Case report: pseudoaneurysm of left ventricle secondary to infective endocarditis complicated by cardiac rupture—a multimodality imaging approach

**Authors:** Sara Ruggerini, Andrea Venturelli, Alberto Giovanni Tripodi, Carlotta Brega

PMC · DOI: 10.1093/ehjcr/ytae318 · European Heart Journal. Case Reports · 2024-07-02

## TL;DR

A 69-year-old woman with infective endocarditis developed a rare left ventricular pseudoaneurysm, which was diagnosed and treated using advanced imaging techniques.

## Contribution

This case report highlights the use of multimodality imaging in diagnosing and managing a rare and life-threatening cardiac complication of infective endocarditis.

## Key findings

- Pseudoaneurysm of the left ventricle was diagnosed using transoesophageal echocardiography and thoracic CT scan.
- Surgical intervention with a pericardial patch successfully excluded the pseudoaneurysm sac.
- Follow-up imaging confirmed successful treatment with minimal residual complications.

## Abstract

Pseudoaneurysm (PSA) of the left ventricle (LV) is a rare peri-annular complication of infective endocarditis (IE), and it is associated with high risk of free wall rupture. The diagnosis is challenging because the exact incidence and the pathogenesis are still unclear.

A 69-year-old lady underwent prosthetic mitral valve replacement for IE secondary to Staphylococcus aureus sepsis complicated by multiple embolizations. In the post-operative period, the patient developed persistent low-grade fever with negative blood culture. Transoesophageal echocardiography (TOE) revealed complete posterior valve detachment and a PSA sac arising from the antero-lateral commissure; the colour flow Doppler showed massive mitral regurgitation. Thoracic computed tomography (CT) scan confirmed the echo data and the exact localization of the cardiac rupture. The patient underwent reoperation, a pericardial patch was sutured to exclude the PSA sac, and a mechanical prosthesis valve was finally implanted. A follow-up TOE revealed the exclusion of the PSA; two leakages with mild peri-valvular mitral regurgitation were found, with no haemodynamic impact.

In our case, the patient developed a PSA of the LV as a consequence of peri-annular extension of IE on the mitral valve. Pseudoaneurysm is a potentially lethal complication, if not promptly treated. Multimodality imaging including echocardiography and CT scan is recommended, in order to plan surgery ad hoc.

## Linked entities

- **Diseases:** infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** rupture (MESH:D012421), fever (MESH:D005334), PSA (MESH:D017541), mitral regurgitation (MESH:D008944), LV (MESH:D020257), IE (MESH:D004696), cardiac rupture (MESH:D006341), valve detachment (MESH:D012163)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11244180/full.md

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Source: https://tomesphere.com/paper/PMC11244180