Bilateral Lacrimal Gland Lymphoma - Case Presentation

TL;DR

A rare case of bilateral lacrimal gland lymphoma in an elderly man is presented, emphasizing the need for multidisciplinary diagnosis and treatment.

Contribution

This paper adds a rare clinical case of bilateral lacrimal gland lymphoma to the medical literature.

Findings

Bilateral lacrimal gland tumors were diagnosed as diffuse large B-cell non-Hodgkin lymphoma of the MALT type.

Surgical intervention and corticosteroid therapy led to symptom improvement and tumor reduction.

Multidisciplinary evaluation is crucial for diagnosing and managing rare orbital tumors.

Abstract

Lacrimal gland lymphomas are rare orbital tumors, constituting a minor fraction of all orbital and ocular adnexal malignancies. This case study presents an 83-year-old male with bilateral lacrimal gland tumors, more prominent in the left orbit, causing decreased visual acuity, red eye, excessive tearing, and diplopia. Initial ophthalmological evaluations and imaging suggested bilateral lacrimal gland lymphoma, confirmed by histopathology as diffuse large B-cell non-Hodgkin lymphoma of the MALT type. Due to the significant tumor size and risk of visual function loss, surgical intervention was performed, followed by corticosteroid therapy. Postoperatively, a marked improvement in symptoms and a reduction in tumor size were observed. This case underscores the importance of comprehensive diagnostic approaches, including clinical, imaging, and histopathological evaluations, highlighting the need for a multidisciplinary approach in managing rare orbital tumors like lacrimal gland lymphoma. The patient’s postoperative and follow-up care included oncological management to monitor and ensure long-term disease control and patient well-being.

Abbreviations: RE = right eye, LE = left eye, CT = Computer tomography, MRI = Magnetic Resonance Imaging, TOD = intraocular pressure of right eye, TOS = intraocular pressure of left eye, US = ultrasound

Figures