A Unique Case of Intracranial Bifocal Germinoma

TL;DR

This paper reports a rare case of a 17-year-old male diagnosed with bifocal germinoma, a type of brain tumor, and his treatment with chemotherapy and radiotherapy.

Contribution

The novelty lies in presenting a unique clinical case of intracranial bifocal germinoma with detailed diagnostic and treatment outcomes.

Findings

The patient had elevated serum markers beta-hCG and LDH, consistent with germinoma.

Imaging revealed a solid cystic lesion in the sella, parasellar region, and pineal region with calcifications.

The patient underwent chemotherapy and radiotherapy following tumor biopsy confirmation.

Abstract

Primary intracranial germ cell tumors are rare tumors that often occur in children and young adults. We report a case of a 17-year-old male, who presented with vomiting, headache, and blurring of vision of the left eye on the temporal aspect for two months. His biological assessment showed panhypopituitarism. Serum markers showed elevated beta human chorionic gonadotropin and lactate dehydrogenase. A solid cystic lesion was noted on imaging, involving the sella, parasellar region, and pineal region with calcifications within. Diagnosis of bifocal germinoma was confirmed by tumor biopsy. The treatment protocol for the patient involved four cycles of chemotherapy using etoposide and carboplatin, followed by a course of radiotherapy.

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