A rare case of leiomyosarcoma with a pleomorphic component of the sigmoid colon

TL;DR

A rare case of a complex tumor in the colon, diagnosed as leiomyosarcoma with a pleomorphic component, highlights the need for more research on this uncommon cancer type.

Contribution

This paper reports the first documented case of leiomyosarcoma with a pleomorphic component in the colon.

Findings

The tumor had two distinct areas with differing features, diagnosed as leiomyosarcoma with a pleomorphic component.

No prior reports exist on this specific type of tumor in the colon, making its recurrence and metastatic behavior unknown.

The case emphasizes the importance of accumulating more data to improve diagnosis and treatment of such rare tumors.

Abstract

A 66-year-old man presented to our institution with a positive fecal occult blood test and lower abdominal pain. Although a tumor was found in the sigmoid colon, biopsy and imaging studies failed to enable the diagnosis of the cancer, and the patient underwent surgery for treatment and diagnosis. The tumor had two distinct areas with differing features shown both histopathologically and on imaging; it was thus diagnosed as a leiomyosarcoma of the sigmoid colon with a pleomorphic component. Here, we describe a rare case of leiomyosarcoma of the sigmoid colon with a pleomorphic component. There are no reports of leiomyosarcoma with pleomorphic components arising in the colon in the literature; thus, the recurrence and metastatic characteristics are unknown. Therefore, accumulating cases in the literature may provide valuable insights into diagnosing and treating these rare tumors.

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