# Primary renal mucormycosis in a type 2 diabetic patient: A case report from Syria

**Authors:** Ali Jawad, Zein Alabdin Hannouneh, Hadi Salame, Hussein Taher, Banan Alkharat

PMC · DOI: 10.1016/j.heliyon.2024.e32906 · 2024-06-15

## TL;DR

A rare case of kidney fungal infection in a diabetic patient from Syria is reported, highlighting the challenges in diagnosis and treatment.

## Contribution

This case report presents a rare instance of primary renal mucormycosis in a type 2 diabetic patient from Syria.

## Key findings

- Primary unilateral renal mucormycosis triggered diabetic ketoacidosis in a type 2 diabetic patient.
- The patient developed complications including bronchopleural fistula and a drug-resistant Klebsiella infection.
- Treatment involved surgery, liposomal amphotericin B, and polymyxine E.

## Abstract

Mucormycosis is an opportunistic fungal infection that primarily affects immunocompromised individuals and rarely presents as renal mucormycosis (RM). Diagnosis can be challenging for many physicians. We report a rare case of primary, unilateral RM which triggered diabetic ketoacidosis in a type 2 diabetic patient. The case was later complicated by a bronchopleural fistula and a meropenem-resistant Klebsiella infection. The patient was ultimately treated with surgical intervention, liposomal amphotericin B, and polymyxine E. Early diagnosis and timely treatment of this life-threatening disease and its complications are significant in reducing mortality.

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## Linked entities

- **Chemicals:** liposomal amphotericin B (PubChem CID 44405442), meropenem (PubChem CID 441130)
- **Diseases:** type 2 diabetes (MONDO:0005148), mucormycosis (MONDO:0019136), diabetic ketoacidosis (MONDO:0012819), Klebsiella infection (MONDO:0030603)

## Full-text entities

- **Diseases:** Klebsiella infection (MESH:D007710), diabetic ketoacidosis (MESH:D016883), fungal infection (MESH:D009181), bronchopleural fistula (MESH:D005402), type 2 diabetic (MESH:D003924), Mucormycosis (MESH:D009091)
- **Chemicals:** meropenem (MESH:D000077731), amphotericin B (MESH:D000666), polymyxine E. (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11237967/full.md

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Source: https://tomesphere.com/paper/PMC11237967