Case Series: Pleomorphic adenoma in minor salivary gland

TL;DR

This case series reports two rare instances of pleomorphic adenoma in minor salivary glands, emphasizing the importance of accurate diagnosis for proper treatment.

Contribution

The novelty lies in documenting two unusual cases of pleomorphic adenoma in minor salivary glands with confirmed histopathological diagnosis.

Findings

Two cases of pleomorphic adenoma were identified in minor salivary glands in an 83-year-old man and a 45-year-old woman.

Histopathological confirmation after surgical resection confirmed the diagnosis of pleomorphic adenoma in both cases.

Pleomorphic adenoma in minor salivary glands is rare, occurring in about 10% of cases, and requires proper diagnosis for treatment.

Abstract

Pleomorphic adenomas (PA) are the most prevalent benign salivary gland neoplasms. They may occur at any age, with a peak incidence between 40 and 60 years of age. They are more commonly observed in females (60%). These tumors can arise in both the major and minor salivary glands. Approximately 80% of these tumors are diagnosed in the parotid gland, whereas 10% arise in the minor salivary glands, mainly affecting the palates, followed by the lips and cheeks.

This report describes two cases of unusual lesions that were diagnosed as (PA) in the minor salivary glands in our department via a review of the relevant literature. The first case involved an 83-year-old man who presented with a slow-growing swelling on the right side of the upper lip, and the second case involved a 45-year-old woman who presented with a slow-growing lesion on the palate. The presence of PA was confirmed histopathologically after surgical resection.

Although relatively rare, PA is a benign lesion, the diagnosis of which must be known for appropriate therapeutic management.

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