Uncommon BK polyomaviruses detected in allogeneic hematopoietic cell transplant recipients
Saagar M. Chokshi, Elizabeth A. Odegard, Heidi L. Meeds, Steven B. Kleiboeker, Assem Ziady, Anthony Sabulski, Sonata Jodele, Alix E. Seif, Stella M. Davies, Benjamin L. Laskin, Jason T. Blackard
TL;DR
This study reports rare BK polyomavirus infections in transplant patients, highlighting the need to understand viral diversity in disease.
Contribution
The paper presents near full-length genome sequences of uncommon BKPyV genotype II in transplant recipients in the USA.
Findings
BKPyV genotype II was detected in two allogeneic hematopoietic cell transplant recipients.
This genotype is uncommon in the USA and its role in disease is not well understood.
Abstract
The role of viral diversity in the pathogenesis of BK polyomavirus (BKPyV)-associated disease is poorly understood. Here, we report near full-length BKPyV genome sequences from two allogeneic hematopoietic cell transplant recipients infected with BKPyV genotype II, which is uncommon in the USA.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsPolyomavirus and related diseases · Full-Duplex Wireless Communications · Antenna Design and Analysis