# Hilliard Seigler, M.D. and the origins of kidney transplantation and immunology at Duke

**Authors:** Stuart J. Knechtle, Justin Barr

PMC · DOI: 10.3389/frtra.2023.1196455 · Frontiers in Transplantation · 2023-05-22

## TL;DR

This paper highlights Dr. Hilliard Seigler's key role in establishing kidney transplantation and immunology at Duke University.

## Contribution

It provides insights into Seigler's foundational work through interviews with him.

## Key findings

- Dr. Seigler made significant contributions to the Duke kidney transplantation program.
- His work spanned both surgical and immunological advancements.
- Interviews reveal his pivotal role in the field's development at Duke.

## Abstract

The contributions of Dr. Hilliard Seigler to the founding of the Duke kidney transplantation program were considerable in both surgery and immunology. Some of these highlights are summarized based upon interviews with Dr. Seigler by the authors.

## Full-text entities

- **Genes:** HLA-C (major histocompatibility complex, class I, C) [NCBI Gene 3107] {aka D6S204, HLA-JY3, HLAC, HLC-C, MHC, PSORS1}, HLA-A (major histocompatibility complex, class I, A) [NCBI Gene 3105] {aka HLAA}
- **Diseases:** toxicity (MESH:D064420), hepatorenal failure (MESH:D051437), melanoma (MESH:D008545), cardiac arrest (MESH:D006323), SEOPF (MESH:D000092124)
- **Chemicals:** steroids (MESH:D013256), digoxin (MESH:D004077), azathioprine (MESH:D001379)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615], Homo sapiens (human, species) [taxon 9606], Mus musculus (house mouse, species) [taxon 10090], Pan troglodytes (chimpanzee, species) [taxon 9598]
- **Cell lines:** Chimp — Pan troglodytes (Chimpanzee), Transformed cell line (CVCL_0E95)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11235256/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11235256/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11235256/full.md

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Source: https://tomesphere.com/paper/PMC11235256