Exploring the Link Between Profuse Warts and Hyper-Immunoglobulin E (IgE) Syndrome: A Pediatric Case Report

TL;DR

A young girl with many warts and other symptoms led to a diagnosis of hyper-IgE syndrome, highlighting warts as a potential sign of this immune disorder.

Contribution

This case report highlights the importance of considering hyper-IgE syndrome in patients presenting with profuse warts and associated symptoms.

Findings

Profuse warts can be a clinical sign of hyper-IgE syndrome in pediatric patients.

Pulmonary involvement and growth delays were observed alongside warts in the reported case.

Early recognition of hyper-IgE syndrome is crucial for appropriate management.

Abstract

The relationship between warts and hyper-immunoglobulin E (IgE) syndrome lies in the fact that patients with this syndrome may have recurrent or persistent skin warts because of their immune dysfunction. Therefore, it is important to consider this possibility when evaluating a patient with skin warts, especially if they are associated with other symptoms such as recurrent infections or pulmonary issues. Warts can thus be an important clinical sign indicating the presence of this syndrome. We report the case of a young girl presenting with numerous warts accompanied by pulmonary involvement and weight delay, in whom the diagnosis of hyper IgE syndrome was established.

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