A case report of squamous cell carcinoma mimicking interdigital intertrigo

TL;DR

A case of squamous cell carcinoma was mistaken for a fungal infection, highlighting the importance of accurate diagnosis and proper biopsy techniques.

Contribution

This case report emphasizes the diagnostic challenges of SCC when it mimics interdigital intertrigo and underscores the need for thorough pathological evaluation.

Findings

The patient's lesion was initially misdiagnosed as keratoacanthoma but later confirmed as moderately differentiated SCC.

Diagnostic errors due to inadequate biopsy methods can lead to delayed treatment of SCC.

Surgical resection was effective in treating the confirmed SCC case.

Abstract

Squamous cell carcinoma (SCC), also known as epidermoid carcinoma, represents the most common malignant tumor affecting the nails. A 60-year-old tailor with no significant medical history presented with a three-year history of macerated skin between the toes, previously treated with a topical antifungal. Dermatological examination revealed a verrucous, infected ulceration with infiltrated and hyperkeratotic edges, characterized by a whitish, fissured base. This lesion in the fourth interdigital space and extended onto the dorsal surface of the foot without any other associated symptoms. The clinical diagnosis identified it as a neoplastic ulceration. An initial biopsy found keratoacanthoma but showed no malignant features. However, follow-up biopsy at our department revealed moderately differentiated SCC. Surgical resection was successful in treating our patient. Diagnostic errors due to insufficient understanding of the pathology and inadequate biopsy methods contribute to the progression of SCC. Surgery is the main treatment for such malignant tumors.

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