# Advancing prenatal diagnosis: Echocardiographic detection of Scimitar syndrome in China – A case series

## TL;DR

This study explores how prenatal echocardiography can help diagnose Scimitar syndrome in fetuses, leading to better management and outcomes.

## Contribution

The study presents a case series demonstrating the use of prenatal echocardiography for early detection of Scimitar syndrome in China.

## Key findings

- Six cases of Scimitar syndrome were diagnosed prenatally with associated cardiac abnormalities.
- Post-surgery, all patients had normal pulmonary vein flow and no pulmonary hypertension.
- Combined coronal and sagittal fetal thorax views improved diagnostic accuracy for Scimitar syndrome.

## Abstract

To investigate the clinical value of echocardiographic detection in the prenatal early diagnosis of Scimitar syndrome (SS) in fetuses, and to develop better and more accurate management strategies for improved prognosis.

A retrospective analysis was conducted on medical records and fetal echocardiographic findings of all cases diagnosed as SS between April 1, 2016 and June 1, 2021. To summarize its echocardiographic features and distinguishing points, comprehensive clinical data and prognostic information were gathered.

Six patients were diagnosed with SS during the study period. Major associated abnormalities included atrial septal defect (n = 3), right inferior pulmonary vein anomalies (n = 2), ventricular septal defect (n = 1), and right aortic arch (n = 1). Post-surgery, all patients exhibited unobstructed pulmonary vein flow and absence of pulmonary hypertension. The average follow-up duration was 24 months, during which five infants underwent surgical intervention for SS.

Comprehensive prenatal screening, particularly combined coronal and sagittal views of the fetal thorax, enables accurate diagnosis of right SS. This approach not only aids in timely intervention but also provides crucial prognostic insights for the child’s future well-being.