# Case Report: Chronic pancreatitis in children as the cumulative effect of bilio-pancreatic abnormalities and genetic mutations

## TL;DR

This case report explores chronic pancreatitis in a child linked to genetic mutations and pancreatic duct abnormalities.

## Contribution

The paper presents a unique pediatric case combining PRSS1 mutation and pancreatic duct duplication.

## Key findings

- A 10-year-old boy with PRSS1 mutation and pancreatic duct duplication developed chronic pancreatitis.
- Management strategies for pediatric chronic pancreatitis require careful consideration of genetic and anatomical factors.

## Abstract

Pancreatitis, in general, is a high-morbidity condition. Genetic conditions and anatomic variants are sometimes seen, especially in children, where biliary etiologies and alcohol are less common than in adults. The decision to intervene, the combined operative-endoscopic strategy, and the timing pose unique challenges. We report the case of a 10-year-old boy with PRSS1 mutation and pancreatic duct duplication, discussing the management and reviewing the recent reports in the Literature.