# Importance of Using Angiography for the Early Detection of Chronic Limb Ischemia in Diabetic Foot Wounds

**Authors:** Vivie Tran, Bernardo Galvan, Sachi Khemka, Katherine Holder, Mohammad M Ansari

PMC · DOI: 10.7759/cureus.61906 · Cureus · 2024-06-07

## TL;DR

This paper discusses how early angiography helps detect chronic limb ischemia in diabetic foot wounds, enabling timely and customized treatments to prevent amputation.

## Contribution

The paper emphasizes the importance of early angiography in diabetic patients with PAD for accurate diagnosis and tailored interventions.

## Key findings

- Early angiography enables accurate diagnosis of chronic limb ischemia in diabetic patients.
- Tailored interventions using catheters and stents can prevent limb amputation in PAD patients.
- Misdiagnosis is common due to atypical symptoms, highlighting the need for timely angiography.

## Abstract

Peripheral artery disease (PAD) affects millions of people worldwide, presenting with varying symptom severity, including chronic total occlusion of arteries, and occasionally, limb amputation. There are various interventions, such as atherectomy and the use of drug-coated balloons and stents, which have been developed to revascularize affected ischemic regions. However, each interventional approach must be individualized due to a patient’s unique underlying conditions. Comorbid conditions, especially diabetes, play a significant role in PAD, as poorly controlled diabetes can accelerate PAD progression. For this reason, an early and accurate diagnosis of PAD is crucial, especially when symptoms may present dissimilar to classic PAD symptoms, often leading to misdiagnosis. The presented cases highlight the tailored interventions to revascularize arteries in patients with diabetic foot wounds utilizing catheters, stents, guidewires, and balloons, made possible after early angiogram. These interventions have been promising in treating PAD patients, and highlight the need for early diagnosis and timely and customized interventions to prevent limb amputation and mitigate potential complications.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), amputation (MESH:C565682), occlusion of arteries (MESH:D001157), Diabetic Foot Wounds (MESH:D017719), Chronic Limb Ischemia (MESH:D000089802), ischemic (MESH:D002545), PAD (MESH:D058729)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11227889/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11227889/full.md

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Source: https://tomesphere.com/paper/PMC11227889