# Clinical Efficacy of Scaling and Root Planing With Placental Extract Gel Under Magnification in Chronic Periodontitis Patients: A Split-Mouth Study

**Authors:** Surabhi Bhadauriya, Sanjay Vasudevan, Ajay Reddy Palle, Abhinav Atchuta, Anuradha Singh

PMC · DOI: 10.7759/cureus.61851 · Cureus · 2024-06-06

## TL;DR

This study found that using placental extract gel with scaling and root planing improves treatment outcomes for chronic periodontitis.

## Contribution

The study introduces placental extract gel as an effective adjunct to standard periodontal therapy under magnification.

## Key findings

- Placental extract gel improved pocket probing depth and relative attachment level.
- The gel reduced gingival inflammation and bleeding on probing significantly.
- Results were observed at six weeks and three months post-treatment.

## Abstract

Background

Chronic localized periodontitis is a prevalent and persistent inflammatory condition in which there is the gradual degradation of the gingiva, periodontal ligament fibers, and alveolar bone loss. The objectives of periodontal therapy encompass not solely the elimination of local factors from the periodontal pocket but also the eradication of the dysbiotic microbial milieu to restore periodontal health. The present study aimed to compare the efficacy of scaling and root planing (SRP) with and without the placement of placental extract gel in the therapeutic management of chronic localized periodontitis under magnification.

Materials and methods

The present investigation encompassed 40 sites in 20 systemically healthy patients with chronic localized periodontitis. The allocation of the sites was done randomly, resulting in two distinct groups: group I (test site) and group II (control site). Group I was subjected to SRP, followed by the placement of placental extract gel, while group II solely received SRP. Clinical evaluations of pocket probing depth, plaque index, relative attachment level (RAL), gingival index (GI), and bleeding on probing (BoP) were performed at each site at baseline, six weeks, and three months.

Results

Placental extract gel as an accompaniment to SRP showed significant improvement in clinical parameters like pocket probing depth, RAL, GI, and BoP.

Conclusion

Placental extract gel may significantly act as a local drug delivery agent in the treatment of localized periodontal pockets.

## Linked entities

- **Diseases:** chronic periodontitis (MONDO:0005593)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), Chronic Periodontitis (MESH:D055113), inflammatory (MESH:D007249), periodontal pockets (MESH:D010514), bone loss (MESH:D001847)
- **Chemicals:** Extract Gel (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11227602/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11227602/full.md

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Source: https://tomesphere.com/paper/PMC11227602