# Secretory Meningioma of the Right Frontal Lobe: Clinical Presentation and Pathological Insights

**Authors:** Daniel Markov, Kristian I Bechev, Vladimir Aleksiev, Ilian Koev

PMC · DOI: 10.7759/cureus.61759 · Cureus · 2024-06-05

## TL;DR

This paper reports a rare case of secretory meningioma in the frontal lobe, highlighting its clinical presentation and successful surgical treatment.

## Contribution

The novelty lies in documenting a rare secretory meningioma subtype with detailed clinical and pathological insights.

## Key findings

- The tumor exhibited hyaline fiber production due to epithelial differentiation of meningothelial cells.
- Successful surgical resection was achieved due to the tumor's anatomical location.
- The patient showed a favorable clinical course post-surgery.

## Abstract

This article presents a case study of a rare convexity meningioma located in the frontal lobe of the right cerebellar hemisphere. Meningiomas comprise a substantial part of central nervous system neoplasms and are classified into benign, atypical, or anaplastic categories, each encompassing a variety of histological subtypes, among which the secretory meningioma is notably rare.

A 77-year-old male presented with a clinical history of headache, impaired memory functions, an initial form of apathetic-abulic syndrome, and a single seizure, which were considered to be indicative of epileptic symptoms that had been present for several weeks. The imaging studies conducted showed a convexity tumor characterized by a rounded morphology and homogeneous contrast enhancement, positioned adjacent to the frontal lobe's cortical surface.

This clinical report details the pathology of a secretory type of meningioma, which is distinguished by the atypical epithelial differentiation of meningothelial cells, resulting in hyaline fiber production. The neoplasm's anatomical accessibility permitted successful surgical resection. The tumor's position was appropriate for surgical removal, and the histological variant, along with the patient's favorable clinical course, is of particular scientific interest.

## Linked entities

- **Diseases:** meningioma (MONDO:0003057)

## Full-text entities

- **Diseases:** headache (MESH:D006261), epileptic (MESH:D004827), central nervous system neoplasms (MESH:D016543), seizure (MESH:D012640), Meningioma (MESH:D008579), impaired memory functions (MESH:D008569), apathetic-abulic syndrome (MESH:D013577), neoplasm (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11226565/full.md

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Source: https://tomesphere.com/paper/PMC11226565