# Tumor Growth in Overdrive: Detailing an Aggressive Course of Hepatocellular Carcinoma

**Authors:** Simardeep Singh, Thilini Delungahawatta, Marcos Wolff, Christopher J. Haas

PMC · DOI: 10.1155/2024/4950398 · Case Reports in Hepatology · 2024-06-15

## TL;DR

This paper describes a rapidly progressing case of liver cancer in an elderly patient with metabolic issues.

## Contribution

The novelty lies in documenting an unusually aggressive clinical course of hepatocellular carcinoma with rapid lesion progression.

## Key findings

- Hepatic lesions developed within six days in an 81-year-old female with metabolic abnormalities.
- The patient's condition rapidly declined despite conservative treatment and passed away within three months.
- Initial misdiagnosis as sepsis delayed appropriate cancer management.

## Abstract

Hepatocellular carcinoma ranks as the third leading cause of cancer-related mortality globally. We present a case of a rapidly progressive hepatocellular carcinoma in an 81-year-old female with metabolic abnormalities. The patient initially presented with non-specific signs and symptoms and was managed for sepsis of suspected urinary source. Unresolving laboratory markers led to repeat abdominal imaging demonstrating new hepatic lesions within six days. Biopsy confirmed moderately differentiated hepatocellular carcinoma. The patient received conservative inpatient treatment with recommendation for nutritional and performance status optimization prior to oncologic therapies, however continued to decline and passed away three months later.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Diseases:** oncologic (MESH:D000072716), Hepatocellular Carcinoma (MESH:D006528), hepatic lesions (MESH:D056486), metabolic abnormalities (MESH:D008659), sepsis (MESH:D018805), Tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11226333/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC11226333/full.md

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Source: https://tomesphere.com/paper/PMC11226333