# Perifollicular Melanocyte Regeneration in Bullous Pemphigoid

**Authors:** Isha Jhingan, Nicholas W Oldham, Daniel A Hyman, Jeffrey D McBride, Jarad I Levin

PMC · DOI: 10.7759/cureus.61652 · Cureus · 2024-06-04

## TL;DR

This case report describes melanocyte regeneration in a skin of color patient with bullous pemphigoid, highlighting an atypical presentation and the need for increased awareness.

## Contribution

The report presents a novel observation of perifollicular melanocyte regeneration in a skin of color patient with bullous pemphigoid.

## Key findings

- Perifollicular melanocyte regeneration was observed in a skin of color patient with bullous pemphigoid.
- The report emphasizes the importance of recognizing atypical presentations of bullous pemphigoid in skin of color patients.

## Abstract

Bullous pemphigoid (BP) is an autoimmune skin disorder that causes fluid-filled blisters to appear on various body parts, often preceded by urticaria and pruritis. This case report describes the perifollicular melanocyte regeneration within diseased areas in a skin of color patient with BP. By reviewing the various pathologies that can result in melanocyte destruction and the basic science of melanocyte regeneration, we can better identify and explain this phenomenon to patients and lead to earlier diagnoses. Furthermore, due to the lack of published information on skin conditions in skin of color patients, this report can assist in raising awareness of an atypical BP presentation in the dermatological community.

## Linked entities

- **Diseases:** bullous pemphigoid (MONDO:0019082)

## Full-text entities

- **Diseases:** blisters (MESH:D001768), autoimmune skin disorder (MESH:D012871), BP (MESH:D010391), urticaria (MESH:D014581), pruritis (MESH:D011537)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11223731/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11223731/full.md

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Source: https://tomesphere.com/paper/PMC11223731