# Embolization coils in treating postoperative bronchopleural fistula: a systematic review

**Authors:** Xiaojuan Luo, Ke Zhan, Yang Bai

PMC · DOI: 10.3389/fmed.2024.1364994 · Frontiers in Medicine · 2024-06-20

## TL;DR

This study reviews the use of embolization coils to treat post-surgery bronchopleural fistulas, finding them effective for small fistulas but needing more research.

## Contribution

The study systematically evaluates embolization coils as a bronchoscopic treatment for postoperative BPF, highlighting their efficacy and safety.

## Key findings

- Embolization coils achieved an 80% complete closure rate in small postoperative BPF cases.
- Coil migration occurred in two cases but did not cause respiratory failure or fistula recurrence.
- Larger BPFs over 3 mm and cases with multiple organ failure were not successfully treated.

## Abstract

This study aims to comprehensively evaluate embolization coils in treating postoperative bronchopleural fistula (BPF).

A systematic review based on PubMed, Embase, and The Cochrane Library studies was conducted. All cases receiving embolization coils in treating postoperative BPF were included. The primary outcome was the efficacy of embolization coils in achieving closure of postoperative BPF.

20 patients from 9 studies were included in this systematic review. A median number of 3 (range: 1–10) embolization coils with sealants obtained a complete closure rate of 80% in patients with postoperative BPF with sizes ranging from 2 to 3.1 mm. Three patients with BPF over 3 mm and one with multiple organ failure failed this treatment. Two cases of coil migration were reported without causing respiratory failure or fistula recurrence.

Embolization coils might be considered a safe and effective bronchoscopic treatment for small postoperative BPF of less than 3 mm in size. More extensive and rigorous studies are needed to further evaluate and confirm the optimal use of embolization coils in the context of an alternative to surgical repair.

## Linked entities

- **Diseases:** multiple organ failure (MONDO:0043726)

## Full-text entities

- **Diseases:** multiple organ failure (MESH:D009102), BPF (MESH:D005402), respiratory failure (MESH:D012131)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC11222595/full.md

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Source: https://tomesphere.com/paper/PMC11222595