# Cardiac Myxoid Spindle Cell Tumor in a Neonate

**Authors:** Reza Abbaszadeh, Fatemeh Naderi, Amir Hossein Jalali, Yaser Toloueitabar

PMC · DOI: 10.1155/2024/8630268 · Case Reports in Pediatrics · 2024-06-26

## TL;DR

A neonate with respiratory distress was found to have a rare benign heart tumor, successfully treated with surgery.

## Contribution

This is the first reported case of a benign cardiac myxoid spindle cell tumor in a neonate.

## Key findings

- A neonate was diagnosed with a right atrial myxoid spindle cell tumor confirmed by pathology.
- Successful surgical resection led to normal cardiac structure and function post-treatment.
- Spindle cell tumors in infants can be benign and have favorable outcomes after surgery.

## Abstract

Introduction: Different subtypes of cardiac tumors containing spindle cells have been described as cardiac sarcoma. However, benign types have not been reported so far. We described a neonate with progressive respiratory distress who had a PDA and was finally diagnosed with a right atrial spindle cell tumor. Case Presentation: The patient was a neonate referred with respiratory distress and sepsis. The initial echocardiography demonstrated a small atrial septal defect, patent ductus arteriosus, and a heterogeneous rounded right atrial mass lesion. Pathologic examination confirmed the right atrial myxoid spindle cell tumor without local invasion. Successful mass resection was performed, and follow-up echocardiography revealed normal cardiac structure and function. Conclusion: In infants with manifestations of possible cardiac anomalies, it is necessary to consider other pathologies, such as neoplastic processes. Spindle cell detection in pathology is not ominous all the time, and there are benign subtypes with favorable outcomes after successful surgical resection.

## Linked entities

- **Diseases:** cardiac sarcoma (MONDO:0003354), patent ductus arteriosus (MONDO:0011827), atrial septal defect (MONDO:0006664)

## Full-text entities

- **Diseases:** atrial mass lesion (MESH:C536030), cardiac tumors (MESH:D006338), Cardiac Myxoid Spindle Cell Tumor (MESH:D002277), sepsis (MESH:D018805), atrial septal defect (MESH:D006344), respiratory distress (MESH:D012128), PDA (MESH:D004374), cardiac anomalies (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11221945/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11221945/full.md

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Source: https://tomesphere.com/paper/PMC11221945