# Functional Outcomes of Fluoroscopy-Guided Intra-articular Steroids in Lumbar Facet Arthropathy: A Retrospective Comparative Study of Dexamethasone Versus Triamcinolone Acetonide

**Authors:** Gowtham Gandhi, Prabhu Ethiraj, Manoj K Ramachandraiah, Arun Kumaar

PMC · DOI: 10.7759/cureus.61551 · Cureus · 2024-06-02

## TL;DR

This study compares the effectiveness of two steroids, dexamethasone and triamcinolone acetonide, for treating low back pain from lumbar facet joints, finding that triamcinolone provides better pain relief and functional improvement.

## Contribution

The study provides a direct comparison of functional outcomes between dexamethasone and triamcinolone acetonide for lumbar facet arthropathy.

## Key findings

- Triamcinolone acetonide showed greater pain alleviation and functional improvement compared to dexamethasone.
- Significant differences in pain scores were observed at six months post-injection.
- Triamcinolone was more effective with no reported drug-related complications.

## Abstract

Introduction

Mechanical low back pain frequently originates from the lumbar facet joint (LFJ). Axial low back discomfort can result from osteoarthritis in the LFJ. Depending on the severity of LFJ degeneration, the effect of intra-articular (IA) LFJ corticosteroid injection may vary. For LFJ discomfort, IA block with steroids and local anaesthetics has also been utilised, with varying degrees of success. The main objective of this study was to assess the efficacy of IA steroid injections dexamethasone vs. triamcinolone acetonide for the treatment of LFJ syndrome and to compare functional outcome in terms of Visual Analog Scale (VAS) score, Modified Oswestry Disability Index (MODI) score, and short-form McGill Pain Questionnaire between the two groups.

Methodology

Dexamethasone 8 mg or triamcinolone acetonide 40 mg was given intra-articularly to 27 patients comprising group A and 33 patients comprising group B, respectively (total 60 patients). Before intervention and at one, three, and six months, observation was conducted using the VAS score, short-form McGill pain questionnaire, and MODI score.

Results

There was a significant difference between both the groups after the procedure with pain alleviation and functional improvement, more in the group that received triamcinolone acetonide. A significant difference was observed in all three parameters that assessed pain with differences more pronounced at six months.

Conclusion

Pain reduction and clinical outcomes were better among the group that received triamcinolone acetonide. Injection of a steroid alone is associated with its own side effects. When a lumbar transforaminal epidural injection is used to treat radiculopathy in the lumbar area, particulate medication (triamcinolone) is more effective than non-particulate medication (dexamethasone) with no known drug-related complications.

## Linked entities

- **Chemicals:** dexamethasone (PubChem CID 5743), triamcinolone acetonide (PubChem CID 6436)
- **Diseases:** radiculopathy (MONDO:0002959)

## Full-text entities

- **Diseases:** LFJ degeneration (MESH:C535531), LFJ syndrome (MESH:C563613), osteoarthritis (MESH:D010003), radiculopathy (MESH:D011843), Mechanical low back pain (MESH:D017116), Pain (MESH:D010146)
- **Chemicals:** Triamcinolone Acetonide (MESH:D014222), Steroids (MESH:D013256), Dexamethasone (MESH:D003907), triamcinolone (MESH:D014221)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11220230/full.md

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Source: https://tomesphere.com/paper/PMC11220230