# Mammary Paget’s Disease as a Sign of Local Recurrence Two Decades Following Breast Conservation and Adjuvant Therapy for Early Stage Breast Cancer

## TL;DR

A rare case shows mammary Paget’s disease appearing as a local recurrence of breast cancer over two decades after initial treatment.

## Contribution

This case highlights the rare occurrence of MPD as a late recurrence of breast cancer and underscores the need for continued surveillance.

## Key findings

- MPD can present as a late recurrence of breast cancer even after two decades of remission.
- Non-malignant causes of nipple dermatitis may delay cancer diagnosis in such cases.
- Vigilant cancer surveillance is crucial for presumed cured cancers to ensure timely intervention.

## Abstract

Reports of mammary Paget’s disease (MPD) as a manifestation of breast cancer recurrence are rare. MPD presents a particular challenge when emerging more than two decades after a breast cancer treated with evidence-based therapy. There is a broad spectrum of non-malignant causes for dermatitis of the nipple during the initial presentation that may delay cancer work-up. This case highlights the MPD work-up and management in the context of a personal history of breast cancer. This unique clinical presentation emphasizes the importance of vigilant cancer surveillance for timely intervention, especially for a presumed cured cancer.