# Infliximab-Induced Improvement in Dercum's Disease

## TL;DR

A patient with Dercum's disease showed improvement after treatment with infliximab and methotrexate.

## Contribution

This case report presents a potential new treatment approach for Dercum's disease using infliximab.

## Key findings

- A patient with Dercum's disease showed improvement with infliximab and methotrexate.
- Current treatment for Dercum's disease is limited to pain management.

## Abstract

Dercum’s disease (DD) is a rare and poorly understood disease characterized by obesity and painful lipomas throughout the body. Although the entity is well described in the literature, its etiology, prevalence, and treatment remain unclear. Currently, treatment is focused on pain management. We describe a case of a patient with DD who showed improvement with infliximab and methotrexate.