# Presentation, Diagnosis, and Treatment of a Sporadic Gastrinoma With Liver Metastases

**Authors:** Alisha Jadhav, Mumen Ayyat, Francesco M Serafini

PMC · DOI: 10.7759/cureus.61426 · Cureus · 2024-05-31

## TL;DR

This paper presents a case of a rare pancreatic tumor that spread to the liver and discusses its diagnosis and treatment.

## Contribution

The case highlights the challenges in diagnosing gastrinoma and the importance of surgical treatment for metastases.

## Key findings

- The patient presented with nonspecific symptoms that led to a delayed diagnosis of gastrinoma.
- Surgical resection of the primary tumor and liver metastases was pursued as a curative treatment.
- The case emphasizes the need for early detection and aggressive management of gastrinoma.

## Abstract

A gastrinoma is a rare and potentially deadly tumor. Gastrinomas can be difficult to detect at first, given that affected patients can present with nonspecific symptoms, such as anemia, weight loss, and diarrhea, leading to a large list of differentials. The symptoms can be hard to manage, and the treatment almost always includes surgical intervention. Gastrinomas often metastasize to the liver, in which case, the only curative treatment option is surgical resection of the primary tumor along with as many metastatic lesions as possible. This report reviews the case of a 59-year-old female who presented with symptoms of anemia and an upper gastrointestinal bleed, who was discovered to have a pancreatic gastrinoma with more than 12 liver metastases. It also describes the management of her critical condition, which was used to give her the best chance of survival.

## Linked entities

- **Diseases:** gastrinoma (MONDO:0003523), anemia (MONDO:0002280)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), weight loss (MESH:D015431), Liver Metastases (MESH:D009362), Gastrinomas (MESH:D015408), gastrointestinal bleed (MESH:D006471), anemia (MESH:D000740), diarrhea (MESH:D003967)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11214729/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11214729/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11214729/full.md

---
Source: https://tomesphere.com/paper/PMC11214729