# Hyperosmolar Hyperglycemic State-Induced Hyperviscosity as a Catalyst for Multiple Embolic Strokes

**Authors:** Lorena Escaño, Prarthana Desai

PMC · DOI: 10.7759/cureus.63331 · Cureus · 2024-06-27

## TL;DR

This paper discusses a rare case where a severe hyperglycemic state led to multiple strokes, highlighting the need for better understanding of the associated risks.

## Contribution

The paper presents a rare clinical case linking hyperosmolar hyperglycemic state with multiple embolic strokes.

## Key findings

- An 86-year-old male with HHS developed multiple embolic strokes during hospitalization.
- The case highlights the prothrombotic state associated with HHS and its potential to cause cerebral infarction.
- Clinical vigilance is emphasized for early recognition of stroke in patients with hyperglycemic crises.

## Abstract

Hyperosmolar hyperglycemic state (HHS) is the most serious emergency in patients with uncontrolled diabetes mellitus. It has been associated with a prothrombotic state that increases the risk for ischemia in affected patients. Despite the literature on the risk of ischemic stroke in patients with chronic hyperglycemia being vast, there is not enough documentation on the risk of developing a stroke during a hyperglycemic crisis. We present a rare case of an 86-year-old male who was admitted with HHS whose hospital course was further complicated by multiple embolic strokes.

Prompt recognition of cerebral infarction when it intertwines with HHS remains a challenging task. This case emphasizes the value of clinical vigilance in patients with this hyperglycemic crisis. Further research is needed to better understand what this prothrombotic state truly entails in these patients.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015), ischemic stroke (MONDO:1060198)

## Full-text entities

- **Diseases:** ischemia (MESH:D007511), HHS (MESH:D006944), hyperglycemia (MESH:D006943), stroke (MESH:D020521), cerebral infarction (MESH:D002544), uncontrolled diabetes mellitus (MESH:D003920), Multiple Embolic Strokes (MESH:D000083262)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11214331/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11214331/full.md

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Source: https://tomesphere.com/paper/PMC11214331