# The Right Gastroepiploic Artery as a Potential Organ at Risk in Neoadjuvant Chemoradiation for Esophageal and Gastroesophageal Cancers

## TL;DR

This paper explores minimizing radiation dose to the right gastroepiploic artery during cancer treatment to reduce post-surgery complications.

## Contribution

The study introduces a method to contour and replan radiation doses to protect the RGEA, a potential organ at risk.

## Key findings

- Significant dose reductions to the RGEA were achieved without compromising target coverage.
- Replanning successfully lowered maximal and mean doses, as well as V10Gy and V20Gy parameters.
- The study demonstrates feasibility of protecting the RGEA during chemoradiation.

## Abstract

Background: Preoperative chemoradiation is a standard of care for esophageal and gastroesophageal cancer. A gastric conduit is usually used for anastomosis with the right gastroepiploic artery (RGEA) being the sole arterial supply to the gastric remnant after such surgeries. Hence, lowering the radiation dose to this vessel may lower the risks of postoperative complications related to poor vasculature. Herein, we report our experience in contouring and replanning cases of distal esophageal/gastroesophageal carcinomas so that the radiation doses to the RGEA could be minimized.

Materials and methods: Radiation plans of patients with lower esophageal/gastroesophageal carcinomas were retrieved from our database. Identification and delineation of the RGEA was done and replanning was performed with the aim to keep the maximal and mean doses as well as the V10Gy and V20Gy of the RGEA as low as possible without compromising target volume coverage.

Results: We achieved significant dose reductions in most of the dosimteric parameters in our selected cases without compromising target coverage.

Conclusion: Lowering the dose to the RGEA, a potential organ-at-risk that may impact the postoperative course after neoadjuvant chemoradiation, is feasible.