# Clinical outcomes in newborns of pregnant women with COVID-19: integrative review

**Authors:** Iara Bezerra da Silva Ximenes, Cassiano Richel Ferreira Leal, Odinéia Maria Amorim Batista, Maria Eliete Batista Moura, Maria Zélia de Araújo Madeira, Andreia Rodrigues Moura da Costa Valle, Pedro Emílio Gomes Prates, Álvaro Francisco Lopes de Sousa, Denise de Andrade

PMC · DOI: 10.1590/0034-7167-2023-0400 · 2024-06-28

## TL;DR

This study reviews clinical outcomes in newborns of mothers with COVID-19, finding that most neonates were not infected and had positive outcomes.

## Contribution

The paper provides an integrative review of neonatal outcomes linked to maternal COVID-19, highlighting infection rates and gestational complications.

## Key findings

- 62.5% of studies reported neonatal contamination by COVID-19.
- Prematurity was the most common gestational complication, mentioned in 75% of studies.
- Neonatal death was rare, reported in 25% of the sample.

## Abstract

to analyze clinical outcomes in newborns of pregnant women with COVID-19.

integrative review conducted in PubMed, Web of Knowledge, SCOPUS, CINHAL; 2,111 studies were obtained, and 8 articles comprised the final sample.

clinical outcomes in neonates of pregnant women positive for COVID-19 were classified according to the following categories: a) contamination by COVID-19, reported in 62.5% of the studies; b) hospital discharge due to improvement, mentioned in 37.5% of the articles; c) death, representing rare cases in 25% of the sample. The most prevalent gestational complication was prematurity, mentioned in 75% of the studies. This complication has been observed due to cases of premature rupture of membranes and placental abruption.

despite the knowledge of asymptomatic and mildly symptomatic behavior in neonates, it is important to continue the search for new clinical data, as this public has uncertain reactions to SARS-CoV-2 infection.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096), SARS-CoV-2 (MONDO:0100096)

## Full-text entities

- **Diseases:** premature rupture of membranes (MESH:D005322), prematurity (MESH:C536271), COVID-19 (MESH:D000086382), placental abruption (MESH:D000037), death (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11213543/full.md

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Source: https://tomesphere.com/paper/PMC11213543