# Pheochromocytoma During Pregnancy: A Hidden Cause for Hypertension

**Authors:** Sidonie Monteiro, Raquel Rodrigues, Amélia Almeida, Maria José Monteiro

PMC · DOI: 10.7759/cureus.61286 · 2024-05-29

## TL;DR

Pheochromocytoma, a rare tumor, can cause hypertension during pregnancy and requires careful diagnosis and management to ensure maternal and fetal safety.

## Contribution

The paper highlights the challenges and management strategies for diagnosing and treating pheochromocytoma during pregnancy.

## Key findings

- Pheochromocytoma can mimic pregnancy-related hypertension but is identifiable through paroxysmal symptoms and biochemical testing.
- Alpha-adrenoceptor blockers are recommended for managing catecholamine excess during pregnancy.
- Timely diagnosis and management are critical for obstetric professionals to ensure safe delivery and surgical intervention.

## Abstract

Pheochromocytoma, a rare but potentially serious condition, poses challenges in timely identification, especially during pregnancy due to misconceptions about pregnancy-related hypertension causes. However, paroxysmal symptoms heighten diagnostic suspicion. The diagnosis relies on biochemical confirmation of catecholamine hypersecretion followed by imaging for tumor localization. When diagnosed at or after 24 weeks, alpha-adrenoceptor blockers are recommended during pregnancy to manage catecholamine excess, delaying tumor removal until viability or post-delivery. The rarity of this condition during pregnancy, coupled with diagnostic and management challenges, underscores its importance for obstetric professionals in addressing hypertensive control, delivery timing, and surgical intervention.

## Linked entities

- **Chemicals:** catecholamine (PubChem CID 189460)
- **Diseases:** pheochromocytoma (MONDO:0004974)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), Hypertension (MESH:D006973), Pheochromocytoma (MESH:D010673)
- **Chemicals:** catecholamine (MESH:D002395)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11211965/full.md

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Source: https://tomesphere.com/paper/PMC11211965