# Occurrence of Guillain-Barré Syndrome in the Early Post-operative Period After an Urgent Liver Transplant

**Authors:** Ariel Jasqui-Bucay, Carlos Moctezuma-Velazquez, Geronimo Pacheco-Aispuro, Mario Vilatobá-Chapa, Jonathan Aguirre-Valadez

PMC · DOI: 10.7759/cureus.63304 · 2024-06-27

## TL;DR

A patient who had an urgent liver transplant developed Guillain-Barré syndrome shortly afterward, which is unusual due to high immunosuppression.

## Contribution

Reports a rare case of Guillain-Barré syndrome occurring early after an urgent liver transplant.

## Key findings

- A patient developed Guillain-Barré syndrome shortly after urgent liver transplant.
- This occurred despite high levels of immunosuppression typically preventing such conditions.
- The case highlights the possibility of inflammatory neuropathies post-transplant.

## Abstract

Solid organ transplant recipients are prone to developing a wide range of complications associated with the procedure itself, as well as with immunosuppressants. Guillain-Barré syndrome, which is part of the spectrum of inflammatory neuropathies, is not expected to occur early after organ transplant when immunosuppression is at its highest point. We describe the clinical case of a patient who underwent an urgent liver transplant due to acute liver failure secondary to drug-induced liver injury and developed Guillain-Barré syndrome early after the transplant.

## Linked entities

- **Diseases:** Guillain-Barré syndrome (MONDO:0016218), acute liver failure (MONDO:0019542), drug-induced liver injury (MONDO:0005359)

## Full-text entities

- **Diseases:** Guillain-Barre Syndrome (MESH:D020275), drug-induced liver injury (MESH:D056486), inflammatory neuropathies (MESH:D020330), acute liver failure (MESH:D017114)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11210954/full.md

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Source: https://tomesphere.com/paper/PMC11210954