# Unmasking the Rarity: A Case Report on Type B Lactic Acidosis in Pediatric Acute Lymphoblastic Leukemia

## TL;DR

A 14-year-old girl with leukemia developed a rare type of lactic acidosis, emphasizing the need for early detection and specialized care in pediatric cancer patients.

## Contribution

This case report highlights the rare occurrence of type B lactic acidosis in pediatric ALL and emphasizes the importance of early recognition and tailored management.

## Key findings

- A 14-year-old ALL patient developed type B lactic acidosis during treatment.
- The patient's condition worsened despite initial interventions, showing the severity of the complication.
- The case underscores the need for multidisciplinary approaches in managing complex pediatric cancer cases.

## Abstract

Acute lymphoblastic leukemia (ALL) is the most prevalent pediatric malignancy, accounting for approximately 25% of childhood cancers. Despite significant advancements in treatment protocols, ALL remains a complex disease, often presenting with various complications, including the rare metabolic disturbance of type B lactic acidosis. This case report details the clinical journey of a 14-year-old female with ALL who developed type B lactic acidosis during treatment. The patient presented with intermittent fever, abdominal pain, jaundice, and hepatosplenomegaly, accompanied by severe anemia and thrombocytopenia. Initial management included supportive care and chemotherapy initiation. Despite aggressive interventions, the patient's condition deteriorated, with escalating lactic acidosis and respiratory distress, leading to a critical need for tailored management strategies. This report underscores the importance of early recognition and comprehensive management of type B lactic acidosis in pediatric ALL, highlighting its multifactorial etiology and potentially life-threatening consequences. Enhanced clinical awareness and a multidisciplinary approach are crucial for improving outcomes in such complex cases.