# Is Camphor the Future in Supporting Therapy for Skin Infections?

**Authors:** Anna Duda-Madej, Szymon Viscardi, Małgorzata Grabarczyk, Ewa Topola, Joanna Kozłowska, Wanda Mączka, Katarzyna Wińska

PMC · DOI: 10.3390/ph17060715 · Pharmaceuticals · 2024-05-31

## TL;DR

This review explores camphor's potential as a natural compound for preventing and supporting treatment of skin infections due to its antimicrobial and healing properties.

## Contribution

The paper systematically reviews camphor's physicochemical properties, sources, and antimicrobial efficacy against skin pathogens.

## Key findings

- Camphor exhibits anti-inflammatory, antibacterial, and antifungal properties relevant to skin infections.
- It can be obtained from natural sources or synthesized chemically for use in medical and cosmetic products.
- Camphor's metabolism and interactions with other substances are discussed in the context of skin disease treatment.

## Abstract

The aim of this review is to present the potential application of camphor—a bicyclic monoterpene ketone—in the prevention of skin infections. Skin diseases represent a heterogeneous group of disorders characterized by prolonged symptoms that significantly diminish the quality of life. They affect the dermis, the epidermis, and even subcutaneous tissue. They very often have a bacterial or fungal background. Therapy for dermatological skin disorders is difficult and long-term. Therefore, it is important to find a compound, preferably of natural origin, that (i) prevents the initiation of this infection and (ii) supports the skin’s repair process. Based on its documented anti-inflammatory, antibacterial, antifungal, anti-acne, anesthetic, strengthening, and warming properties, camphor can be used as a preventative measure in dermatological infectious diseases and as a component in medical and cosmetic products. This work discusses the structure and physicochemical properties of camphor, its occurrence, and methods of obtaining it from natural sources as well as through chemical synthesis. The use of camphor in industrial preparations is also presented. Additionally, after a detailed review of the literature, the metabolism of camphor, its interactions with other medicinal substances, and its antimicrobial properties against bacteria and fungi involved in skin diseases are discussed with regard to their resistance.

## Linked entities

- **Chemicals:** camphor (PubChem CID 2537)

## Full-text entities

- **Diseases:** fungal (MESH:D009181), dermatological skin disorders (MESH:D000168), infectious diseases (MESH:D003141), Skin Infections (MESH:D007239), inflammatory (MESH:D007249), Skin diseases (MESH:D012871), acne (MESH:D000152)
- **Chemicals:** Camphor (MESH:D002164), bicyclic monoterpene ketone (-)
- **Species:** Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395]

## Full text

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## Figures

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## References

183 references — full list in the complete paper: https://tomesphere.com/paper/PMC11206849/full.md

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Source: https://tomesphere.com/paper/PMC11206849