# Two Different Tumors and Lung Aspergilloma: An Uncommon Etiopathogenic Association

**Authors:** Vlad Alexandru Ionescu, Gina Gheorghe, Cosmin Adrian, Alexandru Bebliuc, Cezar Pavelescu, Valentin Enache, Florentina Gheorghe, Nicolae Bacalbasa, Camelia Cristina Diaconu

PMC · DOI: 10.3390/medicina60060953 · Medicina · 2024-06-07

## TL;DR

A rare case of three lung-related diseases is presented to explore their possible connections and improve lung cancer prognosis.

## Contribution

The paper reports a unique case combining lung adenocarcinoma, carcinoid tumor, and pulmonary aspergillosis to investigate their potential pathogenic links.

## Key findings

- A patient presented with lung adenocarcinoma, carcinoid tumor, and pulmonary aspergillosis simultaneously.
- The timely detection of both lung malignancies highlights the need for further investigation into their pathogenic connections.
- Understanding these correlations could lead to improved prognosis for lung cancer patients.

## Abstract

Several cases reported in the literature have confirmed the link between pulmonary aspergillosis and various malignant diseases. Furthermore, it has been observed that the correlation between carcinoid tumor and lung adenocarcinoma is quite uncommon. The etiopathogenic mechanisms underlying these correlations remain poorly defined. We present the case of a patient with three of these diseases: a lung adenocarcinoma with a lepidic pattern, a typical carcinoid, and pulmonary aspergillosis. An additional noteworthy aspect of this case pertains to the timely detection of both lung malignancies. Thus, the necessity for further investigation to ascertain the pathogenic connection among the three diseases is underscored. The ultimate objective is to enhance the prognosis of individuals diagnosed with lung cancer, which is a prevailing malignant disease on a global scale.

## Linked entities

- **Diseases:** lung adenocarcinoma (MONDO:0005061), carcinoid tumor (MONDO:0005369), lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** pulmonary aspergillosis (MESH:D055732), Tumors (MESH:D009369), lung adenocarcinoma (MESH:D000077192), Lung Aspergilloma (MESH:D008171), carcinoid (MESH:D002276), lung cancer (MESH:D008175)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11205853/full.md

## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC11205853/full.md

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Source: https://tomesphere.com/paper/PMC11205853