# The Impact of Cardiovascular Antecedents on the Prognosis of COVID-19 Critically Ill Patients

## TL;DR

This study shows that patients with a history of cardiovascular disease had worse outcomes when critically ill with COVID-19.

## Contribution

The study identifies cardiovascular history as a significant risk factor for severe outcomes in critical COVID-19 patients.

## Key findings

- Patients with cardiovascular antecedents had higher mortality and shorter survival in ICU.
- They showed increased inflammation and developed severe forms of the disease more often.
- Cardiovascular patients were younger on average but had worse clinical outcomes.

## Abstract

Background/Objectives: The objective of the study is to analyze the impact of cardiovascular history on mortality in COVID-19 patients, hospitalized in the intensive care unit with indications for continuous positive airway pressure (CPAP) and subsequently mechanical ventilation, without oncological disease. Methods: A retrospective observational study was carried out on a group of 108 critical COVID-19 patients. We compared demographic data, paraclinical and clinical parameters, days of hospitalization, and mortality rate between two groups of patients, one group with a history of cardiovascular disease (81 patients) and a group without a history of cardiovascular disease (27 patients). Results: Patients with cardiovascular antecedents had a higher mortality rate than those without cardiovascular antecedents, presenting severe forms with shorter survival time in the intensive care unit and increased inflammatory evidence. Compared to patients without a history of cardiovascular illness, those with cardiovascular disease had a lower average age, and developed a severe form of COVID-19. Conclusions: Cardiovascular antecedents can worsen the prognosis of patients with COVID-19, requiring a careful screening and multidisciplinary approach.