# The Thyrohyoid Syndrome: Promoting Awareness with a Case Report and Systematic Review of the Literature

## TL;DR

This paper raises awareness about thyrohyoid syndrome, a rare cause of neck pain, through a case report and literature review, emphasizing its diagnosis and treatment.

## Contribution

The paper provides a systematic review and highlights the importance of clinical diagnosis and steroid infiltration for managing thyrohyoid syndrome.

## Key findings

- Thyrohyoid syndrome is a key differential diagnosis for unilateral neck pain.
- Ultrasound is a useful diagnostic tool, while CT scans are unnecessary.
- Local steroid infiltration is effective for treatment and relapse prevention.

## Abstract

Objective: Neck pain is commonly referred to an ENT specialist and can be caused by the little-known inflammatory condition of the lateral thyrohyoid ligament. The pathophysiology of this condition is believed to be inflammation subsequent to over-exertion or cervical trauma. Typically, patients present with chronic unilateral neck pain. Elicitation of localized tenderness over the axis of the lateral thyrohyoid ligament on palpation is a key finding for its diagnosis. We present an unusual case with an acute course and subcutaneous inflammation and discuss its management in an effort to raise awareness for this often-misdiagnosed syndrome. Methods: A systematic literature research on PubMed was performed selecting patients with a definitive diagnosis of thyrohyoid syndrome or lateral thyrohyoid ligament syndrome. Results: We collected 54 cases from three studies. This condition is an important differential diagnosis for acute or chronic antero-lateral or unilateral neck pain. Conclusion: No specific radiological findings are defined and a CT scan is therefore not necessary for its diagnosis, but ultrasound is a useful tool to primarily assess any neck lesion. Once the diagnosis is made, a local infiltration of steroids is the most sustainable treatment option and relapse prevention.