# Mycosis Fungoides Presenting With Multiple Tumors on the Face

**Authors:** Naoki Sasaki, Yoko Akamatsu, Akane Ogaya, Tomoko Oda, Shun Ohmori, Etsuko Okada, Yu Sawada

PMC · DOI: 10.7759/cureus.61164 · 2024-05-27

## TL;DR

An 84-year-old woman with mycosis fungoides showed tumor reduction on her face using a combination of electron beam therapy and bexarotene.

## Contribution

This case demonstrates the effectiveness of electron beam therapy combined with bexarotene for facial tumors in mycosis fungoides.

## Key findings

- Electron beam therapy combined with bexarotene reduced facial tumors in a patient with mycosis fungoides.
- Topical steroids and UVB therapy showed limited improvement in the patient's condition.
- The patient was diagnosed with Stage IIB mycosis fungoides based on biopsy results.

## Abstract

An 84-year-old female experienced progressive erythema on her limbs and chest over the past year. Initially managed with topical steroids, the erythema eventually spread throughout her body, forming erosions. A biopsy confirmed the diagnosis of mycosis fungoides (MF) (Stage IIB, T2bN0M0B0). Treatment with oral bexarotene (300 mg/day) and narrow-band UVB therapy showed limited improvement. Electron beam therapy (30 Gy in 10 fractions) applied to facial and plantar tumors resulted in a reduction of the tumors. This case highlights the treatment of tumors of MF on the face showing the effectiveness of combining electron beam therapy with bexarotene.

## Linked entities

- **Chemicals:** bexarotene (PubChem CID 82146)
- **Diseases:** mycosis fungoides (MONDO:0009691)

## Full-text entities

- **Diseases:** MF (MESH:D009182), erosions (MESH:D014077), facial and plantar tumors (MESH:D005153), Tumors (MESH:D009369), erythema (MESH:D004890)
- **Chemicals:** steroids (MESH:D013256), bexarotene (MESH:D000077610)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11202170/full.md

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Source: https://tomesphere.com/paper/PMC11202170