# Disseminated Cutaneous Mucormycosis Developing in Peristomal Pyoderma Gangrenosum

## TL;DR

A patient with peristomal pyoderma gangrenosum developed disseminated mucormycosis after long-term glucocorticoid therapy, highlighting the need for skin biopsy and vigilance for fungal infections.

## Contribution

The paper emphasizes the importance of skin biopsy in PPG patients with treatment resistance or new symptoms to detect invasive fungal infections.

## Key findings

- Mucormycosis developed in a patient on long-term glucocorticoid therapy for PPG.
- Skin biopsy is crucial for diagnosing invasive fungal infections in resistant PPG cases.
- Long-term corticosteroid use increases the risk of invasive fungal infections.

## Abstract

A patient on long-term glucocorticoid therapy for peristomal pyoderma gangrenosum (PPG) who developed mucormycosis (MM) of the wound with dissemination was presented. The importance of skin biopsy, together with clinical evaluation in patients with PPG who are resistant to conventional therapy or who develop new symptoms related to their PPG is stressed. The risk and pathogenesis of invasive fungal infections with long-term corticosteroid therapy were explored. The epidemiology and detection of mucormycosis is discussed in this article.