# FDG-PET in HIV-Positive Patient with Extranodal Diffuse Large B-Cell Lymphoma

## TL;DR

This paper presents a case of aggressive lymphoma in an HIV-positive patient, showing unusual nerve spread detected by imaging.

## Contribution

The case highlights unique perineural spread of DLBCL in HIV-positive patients using FDG-PET/MRI.

## Key findings

- DLBCL showed multiorgan involvement in an HIV-positive patient.
- FDG-PET/MRI revealed perineural spread in bilateral trigeminal nerves.
- The case demonstrates the utility of imaging in detecting aggressive lymphoma features.

## Abstract

Extranodal diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease process and an aggressive form of non-Hodgkin's lymphoma. We present a case of multiorgan involvement of DLBCL in a patient with documented risk factors, including [
18
F] fluorodeoxyglucose positron emission tomography/magnetic resonance imaging findings highlighting striking perineural spread involving intracranial and extracranial segments of the bilateral trigeminal nerves.