# Lung Metastases in Endometrial Carcinoma: A Deadly Twist

**Authors:** Souvik Sarkar, Ulhas Jadhav, Pankaj Wagh, Jay Bhanushali, Amit Toshniwal, Arman Sindhu, Bingu Shiv Kiran Reddy

PMC · DOI: 10.7759/cureus.61109 · Cureus · 2024-05-26

## TL;DR

A 73-year-old woman with endometrial cancer showed unusual lung symptoms, highlighting the need for thorough evaluation in atypical cases.

## Contribution

The case highlights the rare and aggressive presentation of endometrial carcinoma with lung metastases and atypical symptoms.

## Key findings

- The patient presented with respiratory symptoms leading to the discovery of lung metastasis from endometrial carcinoma.
- Despite prompt diagnosis, the patient's condition rapidly deteriorated, emphasizing the aggressive nature of the disease.
- The case underscores the importance of considering atypical presentations in cancer diagnosis.

## Abstract

This case report describes the clinical course of a 73-year-old postmenopausal female presenting with a persistent cough, breathlessness, and hypertension. Upon examination, she exhibited signs of respiratory distress, prompting transfer to the intensive care unit (ICU) where type 1 respiratory failure was diagnosed. Chest imaging revealed bilateral lung opacities, leading to a diagnosis of lung metastasis. Subsequent screening investigations unveiled endometrial carcinoma with atypical respiratory symptoms, highlighting the importance of thorough evaluation. Despite prompt management and biopsy confirmation, the patient's condition rapidly deteriorated, underscoring the aggressive nature of metastatic endometrial carcinoma. This case underscores the necessity of considering atypical presentations and timely intervention in managing such malignancies.

## Linked entities

- **Diseases:** endometrial carcinoma (MONDO:0002447)

## Full-text entities

- **Genes:** TWIST1 (twist family bHLH transcription factor 1) [NCBI Gene 7291] {aka ACS3, BPES2, BPES3, CRS, CRS1, CSO}
- **Diseases:** respiratory (MESH:D012131), Lung Metastases (MESH:D009362), Endometrial Carcinoma (MESH:D016889), lung opacities (MESH:D008171), cough (MESH:D003371), respiratory distress (MESH:D012128), hypertension (MESH:D006973), breathlessness (MESH:D004417), malignancies (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11197042/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11197042/full.md

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Source: https://tomesphere.com/paper/PMC11197042