# A Case of Well-Differentiated Endometrial Adenocarcinoma in a Postmenopausal Woman

**Authors:** Siddhi Shringi, Anil K Agrawal, K.M. Hiwale, Pravin Gadkari

PMC · DOI: 10.7759/cureus.61070 · Cureus · 2024-05-25

## TL;DR

A postmenopausal woman with abnormal bleeding was diagnosed with endometrial cancer, highlighting the need for timely diagnosis and treatment.

## Contribution

This case report emphasizes the importance of considering endometrial adenocarcinoma in postmenopausal women with abnormal bleeding.

## Key findings

- The patient was diagnosed with well-differentiated endometrial adenocarcinoma following clinical and histopathological evaluation.
- The tumor was staged as pT1b No Mx, FIGO stage II, indicating invasion into the cervix.
- The case highlights the significance of multidisciplinary management for improved patient outcomes.

## Abstract

Endometrial adenocarcinoma is a prevalent malignancy among postmenopausal women, often presenting with symptoms such as abnormal vaginal bleeding and pelvic pain. We present a case of a 60-year-old postmenopausal female who exhibited abnormal vaginal bleeding for three months, accompanied by pelvic pain and unintentional weight loss. Clinical evaluation, including physical examination, imaging studies, and histopathological examination, led to the diagnosis of well-differentiated endometrial adenocarcinoma. The patient underwent an abdominal hysterectomy with bilateral salpingo-oophorectomy, and histopathological analysis confirmed invasive tumor involvement in the lower uterine segment and cervix. The final pathological tumor, node, and metastasis (TNM) staging was reported as pT1b No Mx, FIGO (International Federation of Gynecology and Obstetrics) stage II. This case underscores the importance of considering endometrial adenocarcinoma in the differential diagnosis of postmenopausal bleeding and highlights the significance of timely diagnosis and multidisciplinary management for optimizing patient outcomes.

## Linked entities

- **Diseases:** endometrial adenocarcinoma (MONDO:0005461)

## Full-text entities

- **Diseases:** TNM (MESH:D008207), pelvic pain (MESH:D017699), postmenopausal bleeding (MESH:D006470), weight loss (MESH:D015431), vaginal bleeding (MESH:D014592), malignancy (MESH:D009369), Endometrial Adenocarcinoma (MESH:D016889)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11196016/full.md

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Source: https://tomesphere.com/paper/PMC11196016