# A Rare Case of Unilateral Fetal Cataract and Coincidental Polydactyly in Congenital Toxoplasmosis

**Authors:** Harneet S Randhawa, Jasneet Randhawa, Akshay More, Akshay Jain

PMC · DOI: 10.7759/cureus.61058 · Cureus · 2024-05-25

## TL;DR

This paper reports a rare case of congenital toxoplasmosis with a unilateral fetal cataract and coincidental polydactyly, highlighting the importance of antenatal imaging for diagnosis and counseling.

## Contribution

The novelty is the first reported case of unilateral cataract and coincidental polydactyly in congenital toxoplasmosis.

## Key findings

- The case presented intracranial calcifications, microcephaly, and growth restriction.
- A unilateral cataract developed in the third trimester, a previously unreported feature in congenital toxoplasmosis.
- Post-axial polydactyly was a coincidental finding, not previously associated with this condition.

## Abstract

Congenital toxoplasmosis is caused by transplacental infection of Toxoplasma gondii during pregnancy. We present a case of a congenital toxoplasma with intracranial calcifications, microcephaly, growth restriction, a unilateral cataract that developed in the third trimester, and a coincidental post-axial-polydactyly. Antenatal imaging findings are important to guide further testing and confirmation of diagnosis, it is important to know all possible associations and prognoses for timely counseling, testing, and intervention. To our knowledge, no case has been published with findings of unilateral cataract in congenital toxoplasmosis and associated coincidental polydactyly. Therefore, we wish to add this case to the current scientific literature.

## Linked entities

- **Diseases:** congenital toxoplasmosis (MONDO:0005715)

## Full-text entities

- **Diseases:** microcephaly (MESH:D008831), Cataract (MESH:D002386), intracranial calcifications (MESH:C537905), Coincidental Polydactyly (MESH:D017689), Congenital Toxoplasmosis (MESH:D014125), growth restriction (MESH:D005317)
- **Species:** Toxoplasma gondii (species) [taxon 5811]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11195811/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11195811/full.md

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Source: https://tomesphere.com/paper/PMC11195811