# Testicular Mixed Germ Cell Tumor (TMGCT) Management: Addressing Infection and Tumor Marker Dynamics

## TL;DR

A 23-year-old man with a testicular tumor and infection showed improved symptoms and lower tumor markers after antibiotic treatment.

## Contribution

Highlights how concurrent infections can affect tumor marker levels and clinical presentation in testicular mixed germ cell tumors.

## Key findings

- Antibiotic treatment resolved fever and significantly decreased tumor marker levels.
- Orchidectomy confirmed the diagnosis of mixed germ cell tumor.
- Infection may influence clinical presentation and tumor marker dynamics in germ cell tumors.

## Abstract

We report the case of a 23-year-old male presenting with right testicular swelling, post-coital pain, and fever. Initial MRI and local examination suggested testicular carcinoma. Elevated serum alpha-fetoprotein (AFP) and lactate dehydrogenase (LDH) levels were observed. Biopsy confirmed a mixed germ cell tumor (MGCT). Concurrently, the patient was diagnosed with an infection and treated with antibiotics. Remarkably, following antibiotic therapy, fever resolved, and tumor marker levels significantly decreased. Subsequent orchidectomy confirmed the diagnosis of MGCT. This case underscores the importance of recognizing and treating concurrent infections, which may influence both clinical presentation and tumor marker levels in testicular germ cell tumors.