# Anti-factor H Autoantibody-Associated Hemolytic Uremic Syndrome: A Rare Entity in a Pediatric Patient

## TL;DR

A rare case of hemolytic uremic syndrome in a child is reported, emphasizing the need for early detection of thrombotic microangiopathy.

## Contribution

This case adds to the limited literature on pediatric thrombotic microangiopathy associated with anti-factor H autoantibodies.

## Key findings

- An 11-year-old patient was diagnosed with thrombotic microangiopathy after presenting with hematuria and vomiting.
- The case highlights the importance of considering TMA in pediatric patients with nonspecific symptoms.
- Further research is needed to understand the pathophysiology and management of pediatric TMA.

## Abstract

An 11-year-old patient presented with the primary complaint of hematuria and vomiting. On further investigation and a series of diagnostic tests, including a biopsy and thrombotic microangiopathy (TMA) profile, the patient was diagnosed with thrombotic microangiopathy. TMA is a pathological process involving endothelial cell injury, leading to thrombocytopenia and microangiopathic hemolytic anemia. This case highlights the importance of considering TMA in pediatric patients presenting with nonspecific symptoms, such as loss of appetite. Further research is needed to understand the pathophysiology and optimal management strategies for pediatric TMA. This case adds to the growing body of literature on pediatric TMA and underscores the need for a high index of suspicion in similar clinical scenarios.