# Abstracts From the First Annual Research Day Hosted by the Michigan State University College of Osteopathic Medicine, Novi, Michigan, May 15, 2023

**Authors:** Andrea Amalfitano, Patricia Obando, Rana Ismail, Francis Akenami

PMC · DOI: 10.51894/001c.115618 · 2024-03-27

## TL;DR

This paper summarizes 139 research abstracts presented at the first annual research day at Michigan State University's College of Osteopathic Medicine.

## Contribution

The paper compiles and publishes abstracts from a diverse range of medical research topics presented at a new academic event.

## Key findings

- 139 abstracts were selected through a blinded review process for presentation at the research day.
- 45 authors chose to have their abstracts published in the Spartan Medical Research Journal.
- The abstracts cover basic science, clinical research, case reports, medical education, and quality improvement.

## Abstract

The Spartan Medical Research Journal (SMRJ) is pleased to publish abstracts from the First Annual Research Day hosted by the Michigan State University College of Osteopathic Medicine (MSUCOM), held in Novi, Michigan, on May 15, 2023. Sponsored by MSUCOM, the Statewide Campus System (SCS), and Research, Innovation, and Scholarly Engagement (RISE), this event showcased a total of 139 selected research abstracts following a meticulous blinded review by the MSUCOM Research Day Planning Committee and SMRJ editorial staff. These abstracts were subsequently presented at the MSUCOM First Annual Research Day in 2023, with awards for exceptional oral and poster presentations conferred on May 15, 2023. Of the 139 presentations that were ultimately chosen, 45 authors consented and elected to have their abstracts published in SMRJ.

The abstracts from 2023 encompass a wide array of contemporary medical and clinical subjects, incorporating a variety of research designs that cover basic science, clinical research, case reports, medical education, and quality improvement. While abstracts offer concise overview of research projects or presentations, they do not permit a comprehensive evaluation of the scientific rigor employed in the respective works. Although these abstracts offer preliminary results that may necessitate further refinement and validation, they serve a vital function in disseminating novel research concepts and advancements in the discipline of medicine. This knowledge-sharing promotes meaningful dialogue among researchers, clinicians, and educators, thereby making a valuable contribution to the collective body of knowledge in the fields of medical sciences and osteopathic medicine.
Andrea Amalfitano, DO, PhD
Osteopathic Heritage Foundation Professor of Pediatrics, Microbiology and Molecular Genetics
Professor, BioMolecular Science Gateway
Editor-in-Chief, Spartan Medical Research Journal (SMRJ)
MSU College of Osteopathic Medicine- Statewide Campus System
C. Patricia Obando S., PhD
Associate Dean and DIO, Graduate Medical Education
Associate Professor- MSU College of Osteopathic Medicine- Statewide Campus System
Rana Ismail, PhD, MSc, CPHQ
Director of Research
Editor, Spartan Medical Research Journal (SMRJ)
MSU College of Osteopathic Medicine- Statewide Campus System
Francis Akenami, BMLS, PhD, MSc, FIMLS
Managing Editor
Spartan Medical Research Journal (SMRJ)
MSU College of Osteopathic Medicine- Statewide Campus System

## Full-text entities

- **Genes:** ALPP (alkaline phosphatase, placental) [NCBI Gene 250] {aka ALP, PALP, PLAP, PLAP-1}, GDF2 (growth differentiation factor 2) [NCBI Gene 2658] {aka BMP-9, BMP9, HHT5}, PRUNE1 (prune exopolyphosphatase 1) [NCBI Gene 58497] {aka DRES-17, DRES17, H-PRUNE, HTCD37, NMIHBA, PRUNE}, Cxcl14 (C-X-C motif chemokine ligand 14) [NCBI Gene 57266] {aka 1110031L23Rik, 1200006I23Rik, BMAC, BRAK, KS1, Kec}, AP2B1 (adaptor related protein complex 2 subunit beta 1) [NCBI Gene 163] {aka ADTB2, AP105B, AP2-BETA, CLAPB1}, TTR (transthyretin) [NCBI Gene 7276] {aka AMYLD1, ATTR, CTS, CTS1, HEL111, HsT2651}, IGHE (immunoglobulin heavy constant epsilon) [NCBI Gene 3497] {aka IgE}, Lpar1 (lysophosphatidic acid receptor 1) [NCBI Gene 14745] {aka Edg2, Gpcr26, Kdt2, lpA1, vzg-1}, CDKN2A (cyclin dependent kinase inhibitor 2A) [NCBI Gene 1029] {aka ARF, CAI2, CDK4I, CDKN2, CMM2, INK4}, BTG3 (BTG anti-proliferation factor 3) [NCBI Gene 10950] {aka ANA, ANA/BTG3, APRO4, TOB5, TOB55, TOFA}, GHITM (growth hormone inducible transmembrane protein) [NCBI Gene 27069] {aka DERP2, HSPC282, MICS1, My021, PTD010, TMBIM5}, TGFB1 (transforming growth factor beta 1) [NCBI Gene 7040] {aka CAEND1, CED, DPD1, IBDIMDE, LAP, TGF-beta1}, CXCL14 (C-X-C motif chemokine ligand 14) [NCBI Gene 9547] {aka BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G}, FANCB (FA complementation group B) [NCBI Gene 2187] {aka FA2, FAAP90, FAAP95, FAB, FACB}, Trpv1 (transient receptor potential cation channel, subfamily V, member 1) [NCBI Gene 193034] {aka OTRPC1, TRPV1alpha, TRPV1beta, VR-1, Vr1}, BMPR2 (bone morphogenetic protein receptor type 2) [NCBI Gene 659] {aka BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1}, Rho (rhodopsin) [NCBI Gene 212541] {aka Noerg1, Opn2, Ops, RP4}, BMP10 (bone morphogenetic protein 10) [NCBI Gene 27302], ACVR2B (activin A receptor type 2B) [NCBI Gene 93] {aka ACTRIIB, ActR-IIB, HTX4}, Nfkb1 (nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105) [NCBI Gene 18033] {aka NF-KB1, NF-kappaB, NF-kappaB1, p105, p50, p50/p105}, HLA-C (major histocompatibility complex, class I, C) [NCBI Gene 3107] {aka D6S204, HLA-JY3, HLAC, HLC-C, MHC, PSORS1}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, Srf (serum response factor) [NCBI Gene 20807], Rela (Rela proto-oncogene, NFKB subunit) [NCBI Gene 19697] {aka p65, p65 NF-kappa B, p65 NFkB}, MYH14 (myosin heavy chain 14) [NCBI Gene 79784] {aka DFNA4, DFNA4A, FP17425, MHC16, MYH17, NMHC II-C}, Pir (pirin) [NCBI Gene 69656] {aka 2310042L19Rik, Pirnl}
- **Diseases:** hemorrhagic shock (MESH:D012771), alcoholic liver cirrhosis (MESH:D008104), CARDIAC (MESH:D006331), hypoxic (MESH:D002534), cancer (MESH:D009369), OSA (MESH:C535586), Bladder Cancer (MESH:D001749), CGD (MESH:D006105), Age-Associated Neurodegeneration (OMIM:614298), tachy- cardia (MESH:D004938), disc disease (MESH:D055959), impetigo (MESH:D007169), diarrhea (MESH:D003967), hyperbilirubinemia (MESH:D006932), DIFFERENTIAL EFFECT OF AGE (OMIM:613784), eyelid swelling (MESH:D005141), atrial-esophageal fistula (MESH:D004937), sinus thrombosis (MESH:D012851), hydronephrosis (MESH:D006869), Infectious Diseases (MESH:D003141), CLBP (MESH:D017116), hepatic encephalopathy (MESH:D006501), Infection (MESH:D007239), arthralgias (MESH:D018771), spasm (MESH:D013035), poisoning (MESH:D011041), Head and Neck Cancer (MESH:D006258), disabilities (MESH:D009069), pulmonary embolism (MESH:D011655), Heart Failure (MESH:D006333), PNEUMONIA (MESH:D011014), GENDER (MESH:D019968), Lip Swelling (MESH:D008047), jugular venous distension (MESH:D005925), EOSINOPHILIC ESOPHAGITIS (MESH:D057765), PERIPHERAL (MESH:D010523), INDUCED (MESH:D000092582), perforation (MESH:D057112), autoimmune pathology (MESH:D001327), bone loss (MESH:D001847), abdominal pain (MESH:D015746), encephalopathy (MESH:D001927), splenic infarction (MESH:D013159), AMERICAN (MESH:D006478), overdose (MESH:D062787), cirrhotic liver (MESH:D008103), renal disease (MESH:D007674), corneal opacity (MESH:D003318), gastrointestinal inflammation (MESH:D007249), Chest Pain (MESH:D002637), HEPARIN-INDUCED THROMBOCYTOPENIA (MESH:C562865), cirrhosis (MESH:D005355), gastrointestinal bleed (MESH:D006471), nausea (MESH:D009325), hypoxic respiratory failure (MESH:D012131), constipation (MESH:D003248), Visceral pain (MESH:D059265), neuropathic pain (MESH:D009437), death (MESH:D003643), CAP (MESH:D003147)
- **Chemicals:** tamoxifen (MESH:D013629), isoflurane (MESH:D007530), gadolinium (MESH:D005682), Clindamycin (MESH:D002981), furosemide (MESH:D005665), creatinine (MESH:D003404), voriconazole (MESH:D065819), Ceftriaxone (MESH:D002443), BiMAB (MESH:C000596367), Magnesium (MESH:D008274), fomepizole (MESH:D000077604), tafamidis (MESH:C547076), Levetiracetam (MESH:D000077287), NM (MESH:D008466), TXA (MESH:D014148), warfarin (MESH:D014859), PUFA (MESH:D005231), Heparin (MESH:D006493), Testosterone (MESH:D013739), doxycycline (MESH:D004318), argatroban (MESH:C031942), Vancomycin (MESH:D014640), bilirubin (MESH:D001663), Nicardipine (MESH:D009529), Azithromycin (MESH:D017963), Zosyn (MESH:D000077725), oxalate (MESH:D010070), fondaparinux (MESH:D000077425), prednisone (MESH:D011241), methylprednisolone (MESH:D008775), PTU (MESH:D011441), CP (MESH:C100187), oxylipin (MESH:D054883), acetone (MESH:D000096), spironolactone (MESH:D013148), T (MESH:D014316), SM (MESH:D009151), capsaicin (MESH:D002211), oxygen (MESH:D010100), 99mTc-PYP (MESH:D016698), Ethylene Glycol (MESH:D019855), Lactic acid (MESH:D019344), Hydralazine (MESH:D006830), GnRHA (-), naloxone (MESH:D009270), sodium bicarbonate (MESH:D017693), albuterol (MESH:D000420), Buprenorphine (MESH:D002047), phosphoinositides (MESH:D010716), LPA (MESH:C032881)
- **Species:** Komagataella pastoris (species) [taxon 4922], Dermatophagoides pteronyssinus (European house dust mite, species) [taxon 6956], Human immunodeficiency virus 1 (no rank) [taxon 11676], Malus domestica (apple, species) [taxon 3750], Aspergillus fumigatus (species) [taxon 746128], Human papillomavirus (species) [taxon 10566], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Mus musculus (house mouse, species) [taxon 10090], C. elegans [taxon 328850], Caenorhabditis elegans (species) [taxon 6239], Rattus norvegicus (brown rat, species) [taxon 10116], Mycoplasma (genus) [taxon 2093], Canis lupus familiaris (dog, subspecies) [taxon 9615], Pasteurella multocida (species) [taxon 747], Phleum pratense (timothy, species) [taxon 15957], Legionella (genus) [taxon 445], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685]
- **Cell lines:** BALB/c — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_0184), C57BL/6J — Mus musculus (Mouse), Transformed cell line (CVCL_C0MW), 293FT — Homo sapiens (Human), Transformed cell line (CVCL_6911), Ad5 — Homo sapiens (Human), Transformed cell line (CVCL_0045), AIN-93 — Homo sapiens (Human), Nephropathic cystinosis, Finite cell line (CVCL_CW96), C57BL/6 — Mus musculus (Mouse), Transformed cell line (CVCL_C0MU), B6.Cg — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_C6EU), CHO — Cricetulus griseus (Chinese hamster), Spontaneously immortalized cell line (CVCL_0213), /6N — Mus musculus (Mouse), Transformed cell line (CVCL_D461)

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Source: https://tomesphere.com/paper/PMC11191887