# Isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma: a rare case report

**Authors:** Tegan Lun, Pranavan Palamuthusingam, Nicholas O’Rourke

PMC · DOI: 10.1093/jscr/rjae418 · 2024-06-21

## TL;DR

A 76-year-old woman had a rare recurrence of pancreatic cancer in her abdominal wall, successfully treated with surgery and chemotherapy.

## Contribution

This paper reports a rare case of isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma successfully treated surgically.

## Key findings

- The patient had a 32 mm lesion consistent with metastatic pancreatic adenocarcinoma.
- Surgical resection and adjuvant chemotherapy led to an uncomplicated recovery.
- Histopathology confirmed poorly differentiated pancreatic ductal adenocarcinoma.

## Abstract

A 76-year-old woman was investigated for epigastric pain on a background of a laparoscopic distal pancreatectomy and splenectomy for pancreatic ductal adenocarcinoma 4 years prior. Imaging revealed an isolated 32 mm fluorodeoxyglucose avid lesion contacting both the anterior abdominal wall and greater curvature of the stomach. Immunohistochemistry and fine needle biopsy confirmed a phenotype consistent with metastatic pancreatic adenocarcinoma. Laparoscopic excision of the mass and partial gastrectomy for clearance of margins was performed. Histopathology demonstrated a poorly differentiated pancreatic ductal adenocarcinoma, and the patient received adjuvant gemcitabine/capecitabine following an uncomplicated postoperative course. This article presents a rare case of isolated abdominal wall recurrence of pancreatic ductal adenocarcinoma, which was successfully treated with surgical resection and adjuvant chemotherapy.

## Linked entities

- **Chemicals:** gemcitabine (PubChem CID 60750), capecitabine (PubChem CID 60953)
- **Diseases:** pancreatic ductal adenocarcinoma (MONDO:0005184)

## Full-text entities

- **Diseases:** epigastric pain (MESH:D010146), pancreatic adenocarcinoma (MESH:D010190), pancreatic ductal adenocarcinoma (MESH:D021441)
- **Chemicals:** gemcitabine/capecitabine (-), fluorodeoxyglucose (MESH:D019788)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11190851/full.md

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Source: https://tomesphere.com/paper/PMC11190851