# An Enigmatic Case of Adult-Onset Still's Disease

**Authors:** Yash Duseja, Ayondyuti Bora, Anupam Dutta, Subhalakshmi Das, Samrat Bhattacharjee

PMC · DOI: 10.7759/cureus.60822 · 2024-05-21

## TL;DR

This paper presents a case of a young woman diagnosed with adult-onset Still's disease, an inflammatory condition, and her successful treatment with steroids and methotrexate.

## Contribution

The paper contributes a documented case of AOSD diagnosis and treatment in a young adult.

## Key findings

- The patient met the Yamaguchi criteria for adult-onset Still's disease.
- The patient showed a positive response to treatment with steroids and methotrexate.

## Abstract

An inflammatory condition known as adult-onset Still's disease (AOSD) is typified by quotidian (daily) fevers, arthritis, and a transient rash. This report details the case of a 21-year-old female patient who presented to our hospital with polyarthritis, a red rash, and a high-grade fever for more than three months. History was suggestive of AOSD, which was further proved by investigation and Yamaguchi criteria for AOSD. Steroids and methotrexate were started, to which the patient responded very well and thereafter.

## Linked entities

- **Chemicals:** steroids (PubChem CID 139082353), methotrexate (PubChem CID 4112)
- **Diseases:** adult-onset Still's disease (MONDO:0019355)

## Full-text entities

- **Diseases:** arthritis (MESH:D001168), fever (MESH:D005334), rash (MESH:D005076), AOSD (MESH:D016706), inflammatory condition (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11190625/full.md

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Source: https://tomesphere.com/paper/PMC11190625