TL;DR
This paper discusses how Purkinje cell dysfunction affects sleep in ataxic mice and features an interview with the first author, Luis E. Salazar Leon.
Contribution
The study identifies a link between Purkinje cell dysfunction and disrupted sleep in a mouse model of ataxia.
Findings
Purkinje cell dysfunction disrupts sleep in ataxic mice.
The research was conducted during Luis E. Salazar Leon's PhD in Roy V. Sillitoe's lab.
Abstract
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Luis E. Salazar Leon is first author on ‘ Purkinje cell dysfunction causes disrupted sleep in ataxic mice’, published in DMM. Luis conducted the research described in this article while a PhD student in Roy V. Sillitoe's lab at Baylor College of Medicine, Houston, Texas, USA. After his PhD, he co-founded Sobek AI in Seattle, Washington, USA, and his current interests lie in using generative AI to accelerate and democratize scientific discovery.
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Taxonomy
TopicsSingle-cell and spatial transcriptomics · Genetic Neurodegenerative Diseases · Reinforcement Learning in Robotics