An unusual presentation of fungal brain abscess in immunocompetent host

TL;DR

A young immunocompetent woman developed a rare fungal brain abscess with unusual symptoms and kidney complications, but recovered after treatment.

Contribution

Reports a rare case of fungal brain abscess in an immunocompetent host with atypical clinical features and complications.

Findings

Fungal brain abscess occurred in an immunocompetent individual without known risk factors.

The infection presented with bilateral lower limb weakness, seizures, fever, and acute kidney injury.

The patient improved after abscess drainage and antifungal therapy, with resolution of kidney injury.

Abstract

Focal area of necrosis, with a surrounding membrane within the brain parenchyma, usually resulting from an infectious process or rarely from a traumatic process known as brain abscess. We report a case of young female, who presented with multiple abscess in left frontal and right occipital region of brain, she was otherwise immunocompetent, lacking any known risk factor for opportunistic infection. And this fungal abscess manifest with unusual presentation of bilateral lower limb weakness along with seizures and fever. This infection leads to acute kidney injury (AKI), necessitating kidney replacement therapy (RRT) in term of intermittent hemodialysis (IHD). After drainage of abscess and antifungal therapy, she responded well, her acute kidney injury resolved and she showed clinical and radiological improvement.

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