# Reverse Koebner Phenomenon in a Vitiligo Patient Treated With Radiotherapy

## TL;DR

A 51-year-old woman with vitiligo experienced skin re-pigmentation after radiation therapy for tongue cancer, a rare example of the reverse Koebner phenomenon.

## Contribution

The paper presents a rare clinical case of reverse Koebner phenomenon in a vitiligo patient following radiotherapy.

## Key findings

- The patient showed re-pigmentation of vitiligo-affected skin after radiation therapy.
- This case highlights the rare occurrence of reverse Koebner phenomenon in dermatological conditions.
- Radiation therapy may influence pigmentation in vitiligo patients in unexpected ways.

## Abstract

Radiation-induced hypopigmentation resulting in a skin condition similar to vitiligo is evident in limited studies. In contrast to the typical Koebner phenomenon where new lesions develop at the site of injury, the trauma-induced disappearance of a specific rash in a patient with an already-developed skin disease is seen very rarely. This phenomenon is called "reverse Koebnerization" or "Koebner non-reaction." Herein, we submit a case of a 51-year-old female with already-developed vitiligo who came for treatment for carcinoma of the tongue with radiation therapy. Later, after the treatment, the patient developed a re-pigmentation of her skin.